Teenager Douglas “Doogie” Howser (Neil Patrick Harris) is a child prodigy who graduated from Princeton at age 10 and became a doctor at 16. The young genius is essentially a well-adjusted teenager but is sometimes drawn to “the dark side” by best friend Vincent “Vinnie” Delpino (Max Casella) while living at home with his parents Katherine and Dr. David Howser (Belinda Montgomery and James Sikking).