A tiny town in the South American jungle known as “la ciudad de las estrellas” (the city of stars) has one very understaffed and under-stocked medical clinic. Young doctors Lily Brenner (Caroline Dhavernas), Mina Minard (Mamie Gummer), and Tommy Fuller (Zach Gilford) land there to help those in need. Each is also trying to escape their own personal demons — something they have in common with the physicians they meet in their new South American locale.