NYC cops Mike Dorigan (Derek Cecil) and Zane Marinelli (Mark Ruffalo) are best friends who try to juggle their jobs, personal struggles, and their relationships. Mike is getting cold feet about marrying medical student Elizabeth Waclawek (Poppy Montgomery) and his extra drinking is causing tension between them. Zane’s loving but unstable girlfriend Beatrice Felsen (Heather Burns) reveals that his father is in jail for the murder of his mother and then burns down his apartment. At work, the partners investigate diverse cases like a pigeon serial killer, a suspected child molester, and a shotgun-toting peeping tom.