Look out, Mojo Jojo. The Powerpuff Girls are back! Watch a promo, below. Cartoon Network‘s reimagined Powerpuff Girls TV series premieres Monday, April 4, 2016 at 6:00pm ET/PT. For two weeks, the series will air daily in at that time, before settling into its regular timeslot, Thursdays, at 6:00pm ET/PT, beginning April 21st.

The 2016 voice cast of The Powerpuff Girls stars: Amanda Leighton as Blossom, Kristen Li as Bubbles, and Natalie Palamides as Buttercup. Jennifer Hale is Miss Kean. Roger Jackson voices Mojo Jojo. The narrator, Tom Kenny, also voices the Mayor of Townsville.

Get all the details, excerpted from the Cartoon Network press release:

It’s Time to Save the World… Before Bedtime

Cartoon Network’s All-New “The Powerpuff Girls” Debuts on Monday, April 4

World Premiere Event at the South by Southwest(R) (SXSW(R)) festival on Monday, March 14

Burbank, Calif. – They’re back… Blossom, Bubbles and Buttercup are saving the day in an all-new, reimagined The Powerpuff Girls, only on Cartoon Network! The latest original, animated comedy series from Cartoon Network Studios, The Powerpuff Girls premieres with back-to-back episodes on Monday, April 4 at 6 p.m. (ET, PT). Following this premiere are two action-packed weeks of new episodes (Monday-Friday, April 4 through 15 at 6 p.m. ET, PT), leading into the show’s regular time slot, Thursdays at 6 p.m. (ET, PT), on April 21.

The Powerpuff Girls will kick off its global return to television with a world premiere event on Monday, March 14 at the South by Southwest (SXSW) festival in Austin, Tex. This fan-centric experience will feature a world premiere screening, pre-party and parade with giant-balloon likenesses of all three Powerpuff Girls. Fast on the heels of the U.S. event, premieres will commence in regions around the globe including Europe, Asia and Latin America.

Superhero sisters Blossom, Bubbles and Buttercup are known to their fellow citizens of Townsville as The Powerpuff Girls. Together, they protect their beautiful, bustling metropolis from sinister evildoers, intent on taking over. Juggling school, homework and a regular parade of villains is no easy task, but The Powerpuff Girls are more than up to the challenge. Armed with supercool superpowers and some topnotch teamwork, The Powerpuff Girls, with occasional assistance from Professor Utonium and the Mayor of Townsville, show their hometown and the world that it is possible to save the world before bedtime.

The Powerpuff Girls is produced by Cartoon Network Studios, with Nick Jennings (Adventure Time, SpongeBob SquarePants) serving as executive producer and Bob Boyle (Wow! Wow! Wubbzy!) as co-executive producer.

One of Cartoon Network’s most enduring original series, the initial run of The Powerpuff Girls, created by Craig McCracken, premiered in 1996 and earned two Emmy(R) Awards along with five nominations and countless animation honors throughout its 78-episodes. The series also spawned a feature film with Warner Bros. Pictures in 2002.

With more than $2.5 billion in retail sales generated since its debut, The Powerpuff Girls is one of the top-grossing Cartoon Network brands of all time, and the new series will be supported by a comprehensive consumer products campaign. Cartoon Network recently partnered with designer Jeremy Scott and Moschino on a global fashion collaboration – The Powerpuff Girls x Jeremy Scott – which is now available as part of Moschino’s spring/summer 2016 collection. Global master toy partner Spin Master will debut a full range of products based on the-all new series beginning in fall 2016 at U.S. retailers, and Cartoon Network has enlisted a roster of more than 20 licensing partners to create a well-rounded assortment of products including toys, apparel, publishing, accessories and more all based on the girls.

###

About Cartoon Network

Cartoon Network is Turner’s #1 U.S. ad-supported cable network with kids 6-11. Seen in 192 countries and over 370 million homes, it is an industry leader known for putting its fans at the center of everything by applying creative thinking and innovation across multiple platforms with a global offering of the best in award-winning animated entertainment for kids and families. Home to the original hit series Adventure Time, Steven Universe, We Bare Bears and The Amazing World of Gumball, Cartoon Network also takes its responsibilities to its audience seriously by addressing those issues affecting families with the Stop Bullying: Speak Upcampaign and by promoting education and creative development through their commitment to STEM enterprises and an integral involvement in Computer Science for All, the White House initiative empowering young people to generate skills to thrive in our digital world.

Cartoon Network is part of Turner, a Time Warner company that creates and programs branded news, entertainment, animation and young adult media environments on television and other platforms for consumers around the world.

Are you fan of The Powerpuff Girls TV show? Do you plan to tune in for the Cartoon Network premiere? Let us know, below.