Series Finale:     
Episode #80 — I Say a Little Prayer
Jackie starts the day with a prayer (and pills) at church and is happy that things are good between she, Kevin and the girls. O’Hara makes a surprise visit with son at Fiona’s confirmation. She and Jackie spend the day together and visit All Saints on its closing day.

Jackie learns that she’s gotten the job at Bellevue Hospital and asks Zoey to join her. She makes an excuse to think about it. Later, O’Hara senses something is wrong and Zoey confides everything about Jackie’s actions/behavior and it’s clear O’Hara is hearing this for the first time.

Eddie has secured the help of Barry Wolfe to get him off from the drug dealer charges but it becomes apparent that it’s not going to happen. He’s screwed but refuses to help the police go after Dr. Wu which would lead them to Jackie.

Jackie continues to be very happy about how things are going and O’Hara confronts her. Jackie maintains that everything is better now and she’s at her best when she’s using. This doesn’t sit well with O’Hara.

A bloodied man with a gun runs into the ER, looking for the person that hit him and stole his drugs. Dr. Prince calmly walks up to him and, with the gun to his head, tells the man that he’s the chief of the NYPD. Unless the man leaves, he’s screwed and Prince starts counting to three, giving him one last chance to run. The man runs out and Prince has a long overdue cigarette.

Jackie finds Vinny — the addict the gunman had been looking for — and he’s scared, huddled behind a toilet. She recognizes him as someone she’s helped several times before. Compassionately, she cleans him up and shares that she’s an addict as well. When he leaves, she offers him his belongings which includes his stash but he refuses it. She may have helped an addict get clean. Vinny is the last person helped at All Saints as the doors close forever.

Eddie shows up to celebrate and joins the party. He’s going away to a white collar prison for a year because he wouldn’t rat on Jackie. It will be hard but he has her in his life. Zoey decides to turn down Jackie’s offer, saying that she needs to find her own way.

Jackie has a sweet goodbye with Prince (he thinks she’s his ex-wife as the tumor is taking over) and, while the party in the ER continues, she goes to the bathroom to use some of Vinny’s drugs.

We then see Jackie walking out the hospital doors into a busy New York City — where she takes part in a yoga class in Time Square. Not quite.

We’re then taken back to the hospital where we see that Jackie has collapsed in the ER. Zoey screams for an ambulance to take Jackie to Bellevue but the hospital has shut down after all. Zoey is telling an unresponsive Jackie that “she’s good.” Her eyelids flutter to the sounds of her friend’s voice. All of her friends are gathered around Jackie as she breathes what could be her final breath.First aired: June 28, 2015.